SkinMedica TNS Advanced+ Serum

$295.00 $250.75

  • Improves coarse wrinkles and fine lines
  • Improves sagging skin
  • Boosts Collagen and Elastin
  • Packed with growth-factors, botanicals, and peptides

1 oz

BONUS Gift - Spend $300 on SkinMedica, Get a Free Stay Bright Kit (includes Lumivive AM and PM 0.5 oz each, 2 Ultra Brightening Sheet Masks, and 1 Rose Quartz Facial Roller) - valued at $175. One gift per order. Must spend amount before taxes on SkinMedica. No cash value, no substitutions. While supplies last. First come, first served. 
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Next Generation Growth Factor – Fragrance-Free

SkinMedica TNS Advanced+ Serum is the new powerhouse product to treat your skin. TNS Advanced is a next-generation growth factor serum that acts on multiple levels of the skin to deliver powerful results.

TNS Advanced+ Serum is formulated with TNS-MR and Renessensce Advanced. TNS-MR contains a next-generation growth factor blend that works on multiple levels of the skin and helps improve skin cell renewal, strengthens the skin barrier, supports healthy skin functions, and nourishes your skin. Renessensce (RSC) Advanced is a complex and highly active blend of powerful botanicals, marine extracts, and peptides that help repair the skin, help increase collagen and elastin production, and helps improve cell renewal.

TNS Advanced Serum Features & Benefits:

  • Smooths visible coarse wrinkles and fine lines
  • Clinically proven to address sagging skin
  • Boosts collagen and elastin levels
  • Improves the appearance of skin tone and texture
  • Supports the skin barrier
  • Protects against free-radicals
  • Results starting in as little as two weeks with progressive improvements measured over 24 weeks with no plateau
  • Fragrance-free
  • Lightweight, matte finish

Who is this product great for?
This product is great for patients with aging skin, volume loss, loss of elasticity, fine lines and wrinkles, skin texture and tone irregularities, dryness, and sun damage. It is also great for people with younger skin not yet exhibiting aging symptoms because it helps to delay the onset of signs of skin aging.

TNS Advanced+ Serum Ingredient Highlights:

Chamber 1: 


  • This advanced formula acts on multiple levels of the skin to help get you to your best results. 
  • Next-generation growth factor blend—supports healthy skin functions
  • Innovative peptide complex—nourishes your skin 

Chamber 2: 


Specifically designed to support the results of the growth factor blend, this highly active blend of powerful botanicals, marine extracts, and peptides includes: 

  • French flax seed – Supports repair functions 
  • Spanish marine extract – Supports skin’s renewal processes 
  • Green microalgae –  Supports collagen and elastin levels

SkinMedica TNS Advanced+ Serum Clinical Studies:

  • 6 Years Younger
    A third-party, validated psychometric scale revealed that patients felt they looked up to 6 years younger after 12 weeks.
  • The appearance of Sagging Skin
    Significant improvements in the appearance of sagging skin after 8 weeks.
  • Progressive Improvement
    Subjects felt increasingly more satisfied with continued use measured over 24 weeks.


Frequently Asked Questions:

What are Growth Factors and what do they do?
Growth factors are naturally occurring proteins that help skin regenerate, heal, and stay healthy, they are not Growth Hormones. They are very important for skin rejuvenation as they are responsible for supporting the repair of damaged skin, making components that provide firmness and elasticity to the skin while helping to maintain skin’s protective functions. As we age, our skin produces fewer growth factors, and environmental aggressors like UV rays and pollution help degrade the existing growth factors. The revolutionary growth factors in SkinMedica TNS Advanced+ Serum help rejuvenate the skin, strengthen the skin barrier, improve the tone and texture, softens fine lines and wrinkles, brightens and moisturizes the skin.

For more information about Growth Factors visit: Growth factors and their amazing benefits at Rejuvent Medical Spa.

What skin types should use TNS Advanced Serum?
TNS Advanced Serum can be used on all skin types. TNS Advanced addresses the existing signs of aging in mature skin and helps prevent delay the appearance of aging skin in younger skin.

How should I apply TNS Advanced?
You should apply this product after cleansing and toning and before applying any other product, apply it morning and night. To use this product press the middle of the pump and dispense a single pump onto the back of your hand. Blend the product together and apply to your face avoiding the eyes.

In what order should I apply my SkinMedica products?
Cleanser, TNS Advanced+ Serum, Lumivive, Lytera, Retinol Complex, HA5 Rejuvenating Hydrator, and sunscreen.

Can I use a product rich in Glycolic Acid with this product?
Yes. Always apply TNS Advanced+ after a cleanser. Wait 15 minutes before applying a Glycolic Acid product.

Sometimes products pill on my skin, how do I prevent that?
Cleanse your skin with a product that removes debris, dead cells, and excess sebum. Dry your skin. Wait for 2 to five minutes before applying TNS. Use only one pump of the product. One pump is enough for the entire face as you only need a very thin layer to see results.

What is the difference between TNS Advanced+ Serum, TNS Recovery Complex, and TNS Essential Serum?

The Advanced Option
TNS® Advanced+ Serum

  • Offers the fastest results of our collection, with a visible improvement in just 2 weeks
  • Targets visible signs of aging skin, including coarse wrinkles, fine lines, uneven tone, and texture
  • First growth factor serum to address sagging skin
  • Colorless and fragrance-free
  • Suitable for patients with vitamin C sensitivity

The Classic Option
TNS Essential Serum®

  • Combination of growth factor blend, antioxidants, and peptides addresses fine lines, uneven tone and texture
  • For patients who have a loyalty to this blend
  • Visit TNS Essential Serum page

The Original

TNS Recovery Complex®

  • Provides gradual improvements in the appearance of fine lines and wrinkles
  • Appropriate for patients with the most sensitive skin
  • Visit TNS Recovery Complex page



BD Rewards

Brilliant Distinction Members: You will earn Brilliant Distinction points on your SkinMedica purchase! If you would like to redeem Brilliant Distinction points on your order please call to order 877-800-2147.


Prior to use, invert and tap the top of container several times in palm of hand.

Press on the center of the pump and apply a single pump onto the back of your hand, blend together and apply to the face, neck and décolleté morning and night. As with any skin care product, avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.


Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin

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What others are saying

  1. TNS + does it all for me

    Maria I.

    1- How is your skin? Neither dry nor oily

    2- What is your skin's complexion? Fair

    3- How are your pores? More Noticeable on nose and chin

    4- How is the weather where you live? The weather is not humid or dry

    I am obsessed with how my skin feels three weeks after starting on this product. Yes it is expensive, but wow. No other product gave me these results. My skin looks better and feels smoother and velvety. I am only using this product in the morning now, plus spf. At night I add retinol and eye cream, but now this is the product for me.

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SkinMedica is committed to advancing the science of skin rejuvenation through research and innovation. Their products work with your skin’s natural healing properties to help you achieve transformative results from the inside out. SkinMedica is committed to research and clinical data. Instead of providing quick fixes, they’ve developed products to promote the long-term health of your skin. These medical grade products work synergistically to address skin concerns such as aging, sun damage, acne, hyperpigmentation, loss of firmness, uneven tone and texture. SkinMedica’s age-defying skincare products are rooted in science and deliver transformative results.

Rejuvent Skin Care is an authorized SkinMedica reseller and sells 100% authentic SkinMedica products. Shop SkinMedica.

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