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ZO Skin Health Radical Night Repair


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  • Hight strength retinol
  • Improves skin texture and uneven pigmentation
  • Minimizes fine lines and wrinkles

2 fl oz


  • Buy any sunscreen product, get a ZO Gentle Cleanser travel-size, and 8 EltaMD sunscreen sample sizes valued at $36
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  • Total gift value $470
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ZO Skin Health products can only be sold in physician offices. Please complete an order request form. We will call you to process your order.  ORDER REQUEST

ZO’s High Potency Retinol!

Radical Night Repair contains high-potency microencapsulated 1% retinol to help brighten the skin, even out skin tone, increase cell turnover, and stimulate collagen production. Its strong antioxidant formula prevents accelerated skin aging while restoring the skin barrier to help reverse dry and dull skin. This is a very strong and active product created to help strengthen your skin’s health. It treats the surface of the skin, it is fast-acting and

ZO Skin Health Radical Night Repair Features and Benefits:

  • Innovative formulation ensures stability for maximum anti-aging benefits
  • Helps improve skin’s brightness, reduces brown spots, and provides a more even tone
  • Provides antioxidant protection to neutralize free radical damage
  • Combats irritation to help calm and soothe the skin

Radical Night Repair Key Ingredients:

  • High Ppotency Microencapsulated Retinol – Stimulates epidermal renewal and collagen production, and helps even skin tone
  • Vitamins C, E, and A, Edelweiss and Marrubium Vulgare Plant Stem Cells – Provides multiple antioxidant protection to prevent future skin aging
  • Zanthoxylum Bungeanum (sichuan pepper) Fruit Extract, Sunflower Seed Oil, and Rosemary Leaf Extract – Anti-irritant complex suppresses inflammation and redness to restore a more youthful skin tone
  • Glycerin and Plukenetia Volubilis Seed Oil – Hydrates and restores the skin barrier with essential lipids to reverse dry, dull skin

Radical Night Repair contains strong, high-potency Retinol and you must apply sunscreen daily while using this product. Because of its strength, you also might need to acclimate your skin to it. We recommend starting slowly and applying it every two days and slowly increase until you can use it every night. This product might cause redness but once your skin is acclimated the redness will be minimized.

For a milder Retinol try ZO Skin Health Retinol Skin Brightener or for a Retinol that penetrates to the dermis try Wrinkle & Texture Repair.

Frequently Asked Questions

What are the anticipated reactions to this retinol?
You should expect some degree of redness, flakiness, dryness, burning, or stinging. These are all normal reactions when starting retinol. With regular product use, the skin will acclimate, revealing a smoother, more even-toned, and youthful-looking complexion. Pair your retinol with a ZO hydrator to minimize anticipated reactions. Consult a physician for customized retinol protocol. Like prescription retinoic acid, retinol will make your skin more sensitive to the sun so you must wear SPF 30 or higher daily.

What is the difference between Radical Night and Wrinkle and Texture Repair?
Both are strong retinol products. Radical Night Repair is an excellent treatment for the epidermis, it uses a slow-release system that treats the upper layer of the skin, treats fine lines, brightens the skin, exfoliates the epidermis, and improves the skin tone. Wrinkle & Texture Repair contains a rapid-release system that treats the dermis, it is suitable to treat deep wrinkles, acne, texture issues, and boost collagen. it is also the one retinol product that can be mixed with a hydroquinone blender like Pigment Control and Blending Creme.

Apply to clean, dry skin. You might have to acclimate to this product, so start applying every 2 days until your skin acclimates. As it gets used to the product and there is less irritation increase usage to every other day until you can use it every night.

You must use a sunscreen with SPF 30+ when using this product.

Cyclopentasiloxane, Dimethicone Crosspolymer, Dimethicone, Prunus Amygdalus Dulcis (Sweet Almond) Oleosomes, Aqua/Water/Eau, Glycerin, Polysorbate 20, Retinol, Plukenetia Volubilis Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Leontopodium Alpinum Meristem Cell Culture, Marrubium Vulgare Meristem Cell Culture, Zanthoxylum Bungeanum Fruit Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Zea Mays (Corn)Oil, Lecithin, Diisopropyl Adipate, Tocopheryl Acetate, Ascorbyl Palmitate, Ascorbic Acid, Tocopherol, Sodium Sulfite, BHT, Beta-Carotene, Caprylyl Glycol, Fragrance (Parfum), Citral, Geraniol, Phenoxyethanol, Chlorphenesin.

Ingredients may change, refer to packaging for the most current information.

  • 2 fl oz

Skin Type
  • Acne Prone

  • Aging Skin
  • Combination
  • Congested
  • Dry
  • Mature
  • Normal
  • Oily
  • Pigment
  • Sun Damaged
  • Wrinkled
Product Type
  • Face Treatments & Serums

  • Lighteners/Brighteners
  • Moisturizers
  • Age Spots

  • Aging Skin
  • Brown Pigmentation
  • Dark Spots
  • Hyperpigmentation
  • Melasma
  • Neck Aging
  • Photodamage
  • Red and Brown Pigmentation
  • Sun Damage
  • Sun Spots
  • Uneven Tone
Ingredient Preference
  • CoQ10

  • Gluten-Free
  • Peptides
  • Retinol
  • Vitamin A
  • Vitamin C
  • Vitamin E
  • Back

  • Décolleté
  • Face
  • Neck
  • Lotion

  • Serums

ZO Skin Health was created to provide physicians and patients with the world’s most innovative and effective skin health solutions. Guided by Dr. Zein Obagi, a practicing dermatologist, their product development team is constantly reviewing market trends, sourcing new ingredients, and formulating products that will provide you with visible results. The dynamic bond between science and skin health is the essence of ZO Skin Health. Their comprehensive and continuous work in skin health solutions utilizes the best of what science has to offer to improve our skin’s natural functions that prevent or resolve many disorders.

Rejuvent is an authorized ZO reseller and sells 100% authentic ZO products. ZO products are only available for sale in-office. If you are our patient please call 480-889-8880 or 877-800-2147. Shop ZO Skin Health.

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5 out of 5 stars

3 reviews

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What others are saying

  1. It really works!!

    Jessica A.

    1- How is your skin? Neither dry nor oily

    2- What is your skin's complexion? Medium

    3- How are your pores? Small

    4- How is the weather where you live? The weather is not humid or dry

    I finally broke down and tried this product and wish I would’ve started using it sooner. It works exactly like it says it does! Highly recommend!

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  2. One of the best high-dose retinol products on the market!

    Logan P.

    1- How is your skin? Neither dry nor oily

    2- What is your skin's complexion? Fair

    3- How are your pores? More Noticeable on nose and chin

    I love this combination of high-dose retinol, with botanicals. My skin has a lot of experience with retinol, but I find this particular combination very effective and easy on the skin. Highly recommend. ZO products are the best.

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  3. LOVE the consistency!!

    Jacquelyn B.

    1- How is your skin? Oily in the t-zone

    2- What is your skin's complexion? Medium

    3- How are your pores? Some large, some small

    4- How is the weather where you live? The weather is dry

    Because of COVID, I’ve had some struggles finding products I need. I had been using an older Obagi Tretinoin .05% and wanted to upgrade to the ZO version of Tretinoin…but I couldn’t find it. So because ZO products have done WONDERS for my acne and overall texture I figured it wouldn’t hurt to try this retinol product. I had used a moistuizer from another brand that had this amazing silicone consistency that I have never been able to find in any other product…..until now! I LOVE how buttery smooth this feels on my skin, and although I only use this at night I love how filling it is for the pores. Your skin looks so smooth with this on at night and you don’t look overly shiny. Love, love love!

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